Pd(quinox)-catalyzed allylic relay Suzuki reactions of secondary homostyrenyl tosylates via alkene-assisted oxidative addition
نویسندگان
چکیده
منابع مشابه
Pd(Quinox)-Catalyzed Allylic Relay Suzuki Reactions of Secondary Homostyrenyl Tosylates via Alkene-Assisted Oxidative Addition.
Pd-catalyzed allylic relay Suzuki cross-coupling reactions of secondary alkyl tosylates, featuring a sterically-hindered oxidative addition and precise control of β-hydride elimination, are reported. The identification of a linear free energy relationship between the relative rates of substrate consumption and the electronic nature of the substrate alkene suggests that the oxidative addition re...
متن کاملSynthesis of chromans via Pd-catalyzed alkene carboetherification reactions.
A new method for the construction of 2-substituted and 2,2-disubstituted chromans via Pd-catalyzed carboetherification reactions between aryl/alkenyl halides and 2-(but-3-en-1-yl)phenols is described. These reactions effect formation of a C-O bond and a C-C bond to afford the chroman products in good yield, and also provide stereoselective access to tricyclic chroman derivatives.
متن کاملTransition metal-catalyzed allylic substitution reactions with unactivated allylic substrates.
The transition metal-catalyzed allylic substitution of unactivated allylic substrates (allylic alcohols, allylic ethers and allylic amines) is rapidly becoming an important area of research. There are several advantages to using these substrates in allylic substitution reactions: the use of unactivated alcohols minimizes the production of waste by-products and reaction steps; and allylic ethers...
متن کاملSynthesis of heterocycles via palladium-catalyzed oxidative addition.
Palladium-catalyzed processes have proven to be a powerful and useful tool for the synthesis of heterocycles. Palladium has found such wide utility because it affects an extraordinary number of very different reactions, including many carbon-carbon bond-forming reactions, under relatively mild reaction conditions. Furthermore, palladium can usually be used in only catalytic amounts and tolerate...
متن کاملSteric and Electronic Effects of Benzoferrocenyl Phosphine Ligands on Palladium-Catalyzed Allylic Alkylation and Suzuki Coupling Reactions
Five benzoferrocenyl phosphine ligands with the phosphorus atom attached to the 5-position of the benzoferrocene and some ligand-Mo(CO)5 complexes were prepared and fully characterized; the structure of one ligand was confirmed by X-ray crystallography. These ligands were applied in palladium-catalyzed allylic alkylation and Suzuki coupling of chlorobenzene with phenylboronic acid. Results were...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chem. Sci.
سال: 2014
ISSN: 2041-6520,2041-6539
DOI: 10.1039/c4sc00602j